Similar systolic and diastolic intervals obtained with the two techniques were significantly correlated. Pressure-volume analysis was conducted in parallel as an invasive method of hemodynamic assessment for comparison. Acoustic cardiography analyses were performed prior, during and after coronary occlusion.
Methods and Results: Ten female Swiss large white pigs underwent permanent distal coronary occlusion as a model of acute myocardial ischemia. During myocardial ischemia hemodynamic abnormalities appear in the first minutes and we hypothesize a putative diagnostic role of acoustic cardiography for prompt detection of cardiac dysfunction for future patient management improvement. 5Department of Cardiology, University Hospital Zurich, Zurich, Switzerlandīackground: Acoustic cardiography is a hybrid technique that couples heart sounds recording with ECG providing insights into electrical-mechanical activity of the heart in an unsupervised, non-invasive and inexpensive manner.4Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.3VisCardia, Inc., Portland, OR, United States.2Division of Surgical Research, University Hospital Zurich, Zurich, Switzerland.1Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.Marco Luciani 1*, Matteo Saccocci 1, Shingo Kuwata 1, Nikola Cesarovic 2, Miriam Lipiski 2, Patricia Arand 3, Peter Bauer 3, Andrea Guidotti 1, Evelyn Regar 1, Paul Erne 4, Michel Zuber 5 and Francesco Maisano 1
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